Containment Engineering in Life Science

Elomatic has proven expertise to Design, Engineer, Qualify & Validate facilities suitable for various high potency drug under several containment classifications. We have credential of building facilities suitable for oncology formulations, hormones, steroids, high potent API as well as bio – containment facilities under BSL2/ BSL3/ BSL4 norms. The containment manufacture requires a specialised approach to design & engineering the manufacturing processes, equipment selection and facility design to achieve desired levels of isolation, containment, minimise operator exposure, ensure worker protection and safety.

A robust containment control strategy is essentials as a growing number of pharmaceutical products contain highly potent active pharmaceutical ingredients (HPAPIs) that are capable of targeting disease selectively and more precisely than any other compounds. HPAPIs are more effective medicines that require lower doses and lead to fewer side effects, but also impose manufacturing challenges due to their toxic, highly potent and sensitising nature that can produce adverse health effects with either acute and chronic exposure.

The concept regarding “Containment” derives from the simple consideration of PPE, process engineering, layout, physical infrastructures and process activities that can isolate the first (product) from the other two elements. Facility design, isolation technologies and general production practices can be more restrictive with respect to handling procedures compared to those employed in typical formulation or API manufacture.

An Occupational Exposure Limit (OEL) is typically set by competent national authorities and enforced by legislation to protect occupational safety and health. It is an important tool in risk assessment and in the management of activities involving handling of dangerous substances. There are many dangerous substances for which there are no formal occupational exposure limits (OEL). In these cases, hazard banding or control banding strategies can be used to ensure safe handling.

The established OEL play vital role in creating the containment philosophy and overall design & engineering of the facility, followed by the procedure protocols etc.

From design & engineering point of view, more emphasis is put on overall design & engineering philosophy inclusive of air lock design, HVAC design, personal protective equipment, gowning philosophy, automation, robotics, drain & ETP, selection of equipment, qualification documents, clean utilities, special civil structure design in case of BSL3/ BSL4 facility etc.

There are multiple philosophies adopted by an pharmaceutical organization for manufacturing a potent drug, viz elimination, substitution, modify process, containment, isolation, ventilation/ extraction, standard operating procedures, plant design etc.

Containment Engineering In Life Science

Civil, Structure & Architectural Design (CSA)

Civil, Structure & Architectural Design (CSA) We provides optimized and innovative state […]

Read more
Civil & Structural Design

Civil & Structural Design Our wide range of resources and expertise offer […]

Read more
Architectural Design

Architectural Design “Form Follows Function” as the quote stated by famous architect “Louis […]

Read more
Clean Room Design

Clean Room Design Elomatic has multi decades experience in Design, Engineering & […]

Read more
Process Engineering

Process Engineering Our mission is to make you experience our Process Engineering […]

Read more
Containment Engineering

Containment Engineering The concept regarding “Containment” derives from the simple consideration of PPE, process […]

Read more
Containment In Healthcare & Hospital

Containment In Healthcare & Hospital The robust control of various operations/ activities […]

Read more
Decontamination Design

Decontamination Design Biosafety regulation aims at protecting human health and environment from […]

Read more
HVAC Design

Heating, Ventilation, and Air Conditioning (HVAC) Our HVAC design and engineering expertise […]

Read more
E & I Engineering

Electricals and Instrumentation Engineering (E & I) We provide comprehensive solutions for […]

Read more
Automation Engineering

Automation Engineering Elomatic offers comprehensive know how of automation architecture with various […]

Read more
Mechanical Engineering

Mechanical Engineering Mechanical engineering is lifeline in delivering a comprehensive design, engineering […]

Read more
Mechanical Design

Mechanical Design Over the years, Elomatic’s mechanical engineering have gained extensive experience […]

Read more
EHS Engineering

Environment, Health and Safety Engineering (EHS) EHS services are an integral part […]

Read more
CQV Services

Commissioning, Qualification & Validation Services (CQV) Elomatic follow ICH harmonization guidelines & ISPE Baseline guidelines for […]

Read more
CSV Services

Computer System Validation Services (CSV) Computer System Validation (CSV) is the process of documenting […]

Read more
Project Management

Project Management Consultancy (PMC) is the kick start of implementations activities.

Read more
Documentation Management

Documentation Management A Comprehensive Document Management is achieved using own proprietary software “EloDoc™”. This system […]

Read more
Virtual Walk Through

Virtual Walk Through Elomatic has expertise in creating the “Virtual Walk Through” the facility […]

Read more
EPCM (Turnkey Solution)

Engineering, Procurement and Construction Management (EPCM) – Turnkey Solution Elomatic is the […]

Read more

Intelligent Engineering Company

  +91 22 2583 6164

Copyright © Elomatic Consulting & Engineering Pvt. Ltd. | Privacy Policy